WI → WI · about 176 miles
Milwaukee to La Crosse bus & train schedule
Jefferson Lines and Amtrak run 28 direct buses and trains a week from Milwaukee to La Crosse. The fastest takes 3 hours 19 minutes; the first departure leaves at 8:55 AM and the last at 4:45 PM. The standard fare with Jefferson Lines is $39 one way.
Timetable data from · No schedule changes since at least
- Buses and trains a week
- 28
- Fastest trip
- 3h 19m
- First departure
- 8:55 AM
- Last departure
- 4:45 PM
- Standard fare
- $39
A standard fare is the carrier's published one-way price. Many carriers price by demand, so the fare when you book can be higher or lower. Fares don't include any fees the carrier's ticket site may add; BusSchedules.com adds no fees. Fares for Amtrak aren't listed here.
Timetable
Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Stops | Company | Standard fare & ticket |
|---|---|---|---|---|---|---|
| 8:55 AM | 1:10 PM | 4h 15m | Daily | Milwaukee (Amtrak Intermodal) to La Crosse (U of WI) | Jefferson Lines Full timetable | $39Book (carrier website) |
| 12:49 PM | 4:11 PM | 3h 22m | Daily | Milwaukee to La Crosse | Amtrak Full timetable | Fare not listed, no online booking link |
| 4:45 PM | 8:04 PM | 3h 19m | Daily | Milwaukee to La Crosse | Amtrak Full timetable | Fare not listed, no online booking link |
Route map
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Where to board in Milwaukee Where you get off in La Crosse The route of the busiest trip
Where to board in Milwaukee
Where buses and trains stop in La Crosse
Return trip: La Crosse to Milwaukee
Questions
How long is the bus or train from Milwaukee to La Crosse?
The fastest direct bus or train takes 3 hours 19 minutes; the typical trip is 3 hours 19 minutes.
How much is the bus or train from Milwaukee to La Crosse?
The standard one-way fare with Jefferson Lines is $39. Many carriers price by demand, so the fare when you book can be higher or lower. Fares don't include any fees the carrier's ticket site may add; BusSchedules.com adds no fees. Fares for Amtrak aren't listed here; check its website.
What time is the first departure from Milwaukee to La Crosse?
The earliest departure is at 8:55 AM (Daily) and the last at 4:45 PM (Daily).
Which bus and rail companies go from Milwaukee to La Crosse?
Jefferson Lines and Amtrak run direct buses and trains on this route.
Where do I board in Milwaukee?
Buses and trains to La Crosse leave from Milwaukee (Amtrak Intermodal).