TN → IL · about 448 miles
Manchester to Chicago bus schedule
Greyhound runs 14 direct buses a week from Manchester to Chicago. The fastest takes 12 hours 5 minutes; the first bus leaves at 12:20 AM and the last at 3:10 AM.
Timetable data from · No schedule changes since at least
- Buses a week
- 14
- Fastest trip
- 12h 05m
- First bus
- 12:20 AM
- Last bus
- 3:10 AM
Timetable
Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Stops | Bus company |
|---|---|---|---|---|---|
| 12:20 AM | 1:15 PM | 12h 55m | Daily | Manchester Shell to Chicago 95th / Dan Ryan | Greyhound Full timetable |
| 3:10 AM | 3:15 PM | 12h 05m | Daily | Manchester Shell to Chicago Bus Station | Greyhound Full timetable |
Route map
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Where to board in Manchester Where you get off in Chicago The route of the busiest trip
Where to catch the bus in Manchester
- Manchester Shell Map of Manchester Shell (Google Maps)
Where the bus stops in Chicago
Return trip: Chicago to Manchester
Questions
How long is the bus from Manchester to Chicago?
The fastest direct bus takes 12 hours 5 minutes.
What time is the first bus from Manchester to Chicago?
The earliest departure is at 12:20 AM (Daily) and the last at 3:10 AM (Daily).
Which bus companies go from Manchester to Chicago?
Greyhound runs direct buses on this route.
Where do I catch the bus in Manchester?
Buses to Chicago leave from Manchester Shell.