PA → IN · about 495 miles
Harrisburg to Indianapolis bus schedule
Greyhound runs 14 direct buses a week from Harrisburg to Indianapolis. The fastest takes 13 hours 20 minutes; the first bus leaves at 2:50 PM and the last at 7:50 PM.
Timetable data from · No schedule changes since at least
- Buses a week
- 14
- Fastest trip
- 13h 20m
- First bus
- 2:50 PM
- Last bus
- 7:50 PM
Timetable
Every bus leaves from Harrisburg Market St Train Station and arrives at Indianapolis Bus Station. Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Bus company |
|---|---|---|---|---|
| 2:50 PM | 4:10 AM +1 day | 13h 20m | Daily | Greyhound Full timetable |
| 7:50 PM | 9:20 AM +1 day | 13h 30m | Daily | Greyhound Full timetable |
Route map
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Where to board in Harrisburg Where you get off in Indianapolis The route of the busiest trip
Where to catch the bus in Harrisburg
Where the bus stops in Indianapolis
Return trip: Indianapolis to Harrisburg
Questions
How long is the bus from Harrisburg to Indianapolis?
The fastest direct bus takes 13 hours 20 minutes.
What time is the first bus from Harrisburg to Indianapolis?
The earliest departure is at 2:50 PM (Daily) and the last at 7:50 PM (Daily).
Which bus companies go from Harrisburg to Indianapolis?
Greyhound runs direct buses on this route.
Where do I catch the bus in Harrisburg?
Buses to Indianapolis leave from Harrisburg Market St Train Station.