MI → KY · about 313 miles
Detroit to Louisville bus schedule
Greyhound runs 14 direct buses a week from Detroit to Louisville. The fastest takes 7 hours 25 minutes; the first bus leaves at 1:50 PM and the last at 7:30 PM.
Timetable data from · No schedule changes since at least
- Buses a week
- 14
- Fastest trip
- 7h 25m
- First bus
- 1:50 PM
- Last bus
- 7:30 PM
Timetable
Every bus leaves from Detroit Bus Station and arrives at Louisville Bus Station. Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Bus company |
|---|---|---|---|---|
| 1:50 PM | 9:55 PM | 8h 05m | Daily | Greyhound Full timetable |
| 7:30 PM | 2:55 AM +1 day | 7h 25m | Daily | Greyhound Full timetable |
Route map
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Where to board in Detroit Where you get off in Louisville The route of the busiest trip
Where to catch the bus in Detroit
Where the bus stops in Louisville
- Louisville Bus Station Map of Louisville Bus Station (Google Maps)
Return trip: Louisville to Detroit
Questions
How long is the bus from Detroit to Louisville?
The fastest direct bus takes 7 hours 25 minutes.
What time is the first bus from Detroit to Louisville?
The earliest departure is at 1:50 PM (Daily) and the last at 7:30 PM (Daily).
Which bus companies go from Detroit to Louisville?
Greyhound runs direct buses on this route.
Where do I catch the bus in Detroit?
Buses to Louisville leave from Detroit Bus Station.