CO → IA · about 607 miles
Denver to Des Moines bus schedule
Greyhound runs 7 direct buses a week from Denver to Des Moines. The fastest takes 13 hours; every bus leaves at 6:55 PM.
Timetable data from · No schedule changes since at least
- Buses a week
- 7
- Fastest trip
- 13h 00m
- Leaves at
- 6:55 PM
Timetable
Every bus leaves from Denver Union Station Bus Concourse and arrives at Des Moines. Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Bus company |
|---|---|---|---|---|
| 6:55 PM | 8:55 AM +1 day | 13h 00m | Daily | Greyhound Full timetable |
Route map
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Where to board in Denver Where you get off in Des Moines The route of the busiest trip
Where to catch the bus in Denver
Where the bus stops in Des Moines
- Des Moines bus stop Map of Des Moines bus stop (Google Maps)
Return trip: Des Moines to Denver
Questions
How long is the bus from Denver to Des Moines?
The fastest direct bus takes 13 hours.
What time is the first bus from Denver to Des Moines?
Every departure is at 6:55 PM (Daily).
Which bus companies go from Denver to Des Moines?
Greyhound runs direct buses on this route.
Where do I catch the bus in Denver?
Buses to Des Moines leave from Denver Union Station Bus Concourse.