FL → SC · about 354 miles
Daytona Beach to Florence bus schedule
FlixBus runs 5 direct buses a week from Daytona Beach to Florence. The fastest takes 7 hours 15 minutes; every bus leaves at 4:50 PM.
Timetable data from · No schedule changes since at least
- Buses a week
- 5
- Fastest trip
- 7h 15m
- Leaves at
- 4:50 PM
Timetable
Every bus leaves from Daytona Beach Cornerstone Blvd and arrives at Florence Sc. Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Bus company |
|---|---|---|---|---|
| 4:50 PM | 12:05 AM +1 day | 7h 15m | Mon, Thu, Fri, Sat, Sun | FlixBus Full timetable |
Route map
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Where to board in Daytona Beach Where you get off in Florence The route of the busiest trip
Where to catch the bus in Daytona Beach
Where the bus stops in Florence
Return trip: Florence to Daytona Beach
Questions
How long is the bus from Daytona Beach to Florence?
The fastest direct bus takes 7 hours 15 minutes.
What time is the first bus from Daytona Beach to Florence?
Every departure is at 4:50 PM (Mon, Thu, Fri, Sat, Sun).
Which bus companies go from Daytona Beach to Florence?
FlixBus runs direct buses on this route.
Where do I catch the bus in Daytona Beach?
Buses to Florence leave from Daytona Beach Cornerstone Blvd.