IL → MO · about 147 miles
Champaign to St. Louis bus schedule
FlixBus runs 15 direct buses a week from Champaign to St. Louis. The fastest takes 3 hours 15 minutes; the first bus leaves at 3:05 AM and the last at 7:50 PM.
Timetable data from · Schedule last changed
- Buses a week
- 15
- Fastest trip
- 3h 15m
- First bus
- 3:05 AM
- Last bus
- 7:50 PM
Timetable
Every bus leaves from Champaign Intermodal Trans Ctr and arrives at St Louis Bus Station. Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Bus company |
|---|---|---|---|---|
| 3:05 AM | 6:20 AM | 3h 15m | Mon, Thu, Fri, Sat, Sun | FlixBus Full timetable |
| 12:20 PM | 3:40 PM | 3h 20m | Mon, Thu, Fri, Sat, Sun | FlixBus Full timetable |
| 7:50 PM | 11:20 PM | 3h 30m | Mon, Thu, Fri, Sat, Sun | FlixBus Full timetable |
Route map
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Where to board in Champaign Where you get off in St. Louis The route of the busiest trip
Where to catch the bus in Champaign
- Champaign-Urbana Map of Champaign-Urbana (Google Maps)
Where the bus stops in St. Louis
- St Louis Bus Station Map of St Louis Bus Station (Google Maps)
Return trip: St. Louis to Champaign
Questions
How long is the bus from Champaign to St. Louis?
The fastest direct bus takes 3 hours 15 minutes; the typical trip is 3 hours 20 minutes.
What time is the first bus from Champaign to St. Louis?
The earliest departure is at 3:05 AM (Mon, Thu, Fri, Sat, Sun) and the last at 7:50 PM (Mon, Thu, Fri, Sat, Sun).
Which bus companies go from Champaign to St. Louis?
FlixBus runs direct buses on this route.
Where do I catch the bus in Champaign?
Buses to St. Louis leave from Champaign-Urbana.