MN → WI · about 200 miles
Winona to Milwaukee bus & train schedule
Jefferson Lines and Amtrak run 28 direct buses and trains a week from Winona to Milwaukee. The fastest takes 3 hours 56 minutes; the first departure leaves at 11:01 AM and the last at 2:00 PM. The standard fare with Jefferson Lines is $103 one way.
Timetable data from · No schedule changes since at least
- Buses and trains a week
- 28
- Fastest trip
- 3h 56m
- First departure
- 11:01 AM
- Last departure
- 2:00 PM
- Standard fare
- $103
A standard fare is the carrier's published one-way price. Many carriers price by demand, so the fare when you book can be higher or lower. Fares don't include any fees the carrier's ticket site may add; BusSchedules.com adds no fees. Fares for Amtrak aren't listed here.
Timetable
Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Stops | Company | Standard fare & ticket |
|---|---|---|---|---|---|---|
| 11:01 AM | 2:57 PM | 3h 56m | Daily | Winona to Milwaukee | Amtrak Full timetable | Fare not listed, no online booking link |
| 1:41 PM | 5:37 PM | 3h 56m | Daily | Winona to Milwaukee | Amtrak Full timetable | Fare not listed, no online booking link |
| 2:00 PM | 7:30 PM | 5h 30m | Daily | Winona St. University to Milwaukee (Amtrak Intermodal) | Jefferson Lines Full timetable | $103Book (carrier website) |
Route map
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Where to board in Winona Where you get off in Milwaukee The route of the busiest trip
Where to board in Winona
Where buses and trains stop in Milwaukee
Return trip: Milwaukee to Winona
Questions
How long is the bus or train from Winona to Milwaukee?
The fastest direct bus or train takes 3 hours 56 minutes; the typical trip is 3 hours 56 minutes.
How much is the bus or train from Winona to Milwaukee?
The standard one-way fare with Jefferson Lines is $103. Many carriers price by demand, so the fare when you book can be higher or lower. Fares don't include any fees the carrier's ticket site may add; BusSchedules.com adds no fees. Fares for Amtrak aren't listed here; check its website.
What time is the first departure from Winona to Milwaukee?
The earliest departure is at 11:01 AM (Daily) and the last at 2:00 PM (Daily).
Which bus and rail companies go from Winona to Milwaukee?
Jefferson Lines and Amtrak run direct buses and trains on this route.
Where do I board in Winona?
Buses and trains to Milwaukee leave from Winona St. University and Winona Amtrak station.