MS → AL · about 119 miles
Tupelo to Birmingham bus schedule
Greyhound runs 14 direct buses a week from Tupelo to Birmingham. The fastest takes 2 hours 30 minutes; the first bus leaves at 10:55 AM and the last at 11:15 PM.
Timetable data from · No schedule changes since at least
- Buses a week
- 14
- Fastest trip
- 2h 30m
- First bus
- 10:55 AM
- Last bus
- 11:15 PM
Timetable
Every bus leaves from Tupelo Brothers Quick Stop and arrives at Birmingham Central Bus Station. Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Bus company |
|---|---|---|---|---|
| 10:55 AM | 1:25 PM | 2h 30m | Daily | Greyhound Full timetable |
| 11:15 PM | 1:55 AM +1 day | 2h 40m | Daily | Greyhound Full timetable |
Route map
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Where to board in Tupelo Where you get off in Birmingham The route of the busiest trip
Where to catch the bus in Tupelo
- Tupelo Brothers Quick Stop Map of Tupelo Brothers Quick Stop (Google Maps)
Where the bus stops in Birmingham
Return trip: Birmingham to Tupelo
Questions
How long is the bus from Tupelo to Birmingham?
The fastest direct bus takes 2 hours 30 minutes.
What time is the first bus from Tupelo to Birmingham?
The earliest departure is at 10:55 AM (Daily) and the last at 11:15 PM (Daily).
Which bus companies go from Tupelo to Birmingham?
Greyhound runs direct buses on this route.
Where do I catch the bus in Tupelo?
Buses to Birmingham leave from Tupelo Brothers Quick Stop.