AL → MS · about 119 miles
Birmingham to Tupelo bus schedule
Greyhound runs 14 direct buses a week from Birmingham to Tupelo. The fastest takes 2 hours 35 minutes; the first bus leaves at 2:45 AM and the last at 7:00 PM.
Timetable data from · No schedule changes since at least
- Buses a week
- 14
- Fastest trip
- 2h 35m
- First bus
- 2:45 AM
- Last bus
- 7:00 PM
Timetable
Every bus leaves from Birmingham Central Bus Station and arrives at Tupelo Brothers Quick Stop. Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Bus company |
|---|---|---|---|---|
| 2:45 AM | 5:25 AM | 2h 40m | Daily | Greyhound Full timetable |
| 7:00 PM | 9:35 PM | 2h 35m | Daily | Greyhound Full timetable |
Route map
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Where to board in Birmingham Where you get off in Tupelo The route of the busiest trip
Where to catch the bus in Birmingham
Where the bus stops in Tupelo
- Tupelo Brothers Quick Stop Map of Tupelo Brothers Quick Stop (Google Maps)
Return trip: Tupelo to Birmingham
Questions
How long is the bus from Birmingham to Tupelo?
The fastest direct bus takes 2 hours 35 minutes.
What time is the first bus from Birmingham to Tupelo?
The earliest departure is at 2:45 AM (Daily) and the last at 7:00 PM (Daily).
Which bus companies go from Birmingham to Tupelo?
Greyhound runs direct buses on this route.
Where do I catch the bus in Birmingham?
Buses to Tupelo leave from Birmingham Central Bus Station.