MS → TN · about 95 miles
Tupelo to Memphis bus schedule
Greyhound runs 14 direct buses a week from Tupelo to Memphis. The fastest takes 1 hour 50 minutes; the first bus leaves at 5:35 AM and the last at 9:45 PM.
Timetable data from · No schedule changes since at least
- Buses a week
- 14
- Fastest trip
- 1h 50m
- First bus
- 5:35 AM
- Last bus
- 9:45 PM
Timetable
Every bus leaves from Tupelo Brothers Quick Stop and arrives at Memphis Greyhound Bus Station. Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Bus company |
|---|---|---|---|---|
| 5:35 AM | 7:25 AM | 1h 50m | Daily | Greyhound Full timetable |
| 9:45 PM | 11:35 PM | 1h 50m | Daily | Greyhound Full timetable |
Route map
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Where to board in Tupelo Where you get off in Memphis The route of the busiest trip
Where to catch the bus in Tupelo
- Tupelo Brothers Quick Stop Map of Tupelo Brothers Quick Stop (Google Maps)
Where the bus stops in Memphis
Return trip: Memphis to Tupelo
Questions
How long is the bus from Tupelo to Memphis?
The fastest direct bus takes 1 hour 50 minutes.
What time is the first bus from Tupelo to Memphis?
The earliest departure is at 5:35 AM (Daily) and the last at 9:45 PM (Daily).
Which bus companies go from Tupelo to Memphis?
Greyhound runs direct buses on this route.
Where do I catch the bus in Tupelo?
Buses to Memphis leave from Tupelo Brothers Quick Stop.