OH → NY · about 257 miles
Toledo to Buffalo train schedule
Amtrak runs 14 direct trains a week from Toledo to Buffalo. The fastest takes 5 hours 22 minutes; the first train leaves at 2:31 AM and the last at 3:31 AM.
Timetable data from · Schedule last changed
- Trains a week
- 14
- Fastest trip
- 5h 22m
- First train
- 2:31 AM
- Last train
- 3:31 AM
Timetable
Every train leaves from Toledo and arrives at Buffalo Depew Station. Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Rail company |
|---|---|---|---|---|
| 2:31 AM New | 8:53 AM | 6h 22m | Mon | Amtrak Full timetable |
| 3:31 AM | 8:53 AM | 5h 22m | Daily | Amtrak Full timetable |
Route map
The map needs JavaScript.
Where to board in Toledo Where you get off in Buffalo The route of the busiest trip
Where to catch the train in Toledo
- Toledo (Amtrak) Map of Toledo (Amtrak) (Google Maps)
Where the train stops in Buffalo
Return trip: Buffalo to Toledo
Questions
How long is the train from Toledo to Buffalo?
The fastest direct train takes 5 hours 22 minutes; the typical trip is 5 hours 22 minutes.
What time is the first train from Toledo to Buffalo?
The earliest departure is at 2:31 AM (Mon) and the last at 3:31 AM (Daily).
Which rail companies go from Toledo to Buffalo?
Amtrak runs direct trains on this route.
Where do I catch the train in Toledo?
Trains to Buffalo leave from Toledo (Amtrak).