NY → MA · about 263 miles
Syracuse to Boston bus & train schedule
Amtrak, FlixBus, Greyhound and OurBus run 26 direct buses and trains a week from Syracuse to Boston. The fastest takes 6 hours 20 minutes; the first departure leaves at 6:50 AM and the last at 3:55 PM.
Timetable data from · Schedule last changed
- Buses and trains a week
- 26
- Fastest trip
- 6h 20m
- First departure
- 6:50 AM
- Last departure
- 3:55 PM
2 of the 26 buses and trains a week stop at Syracuse Hancock International Airport (SYR).
Timetable
Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Stops | Company |
|---|---|---|---|---|---|
| 6:50 AM | 2:30 PM | 7h 40m | Daily | Syracuse Bus Station to Boston South Station | Greyhound Full timetable |
| 9:00 AM New | 3:20 PM | 6h 20m | Tue, Sat from Nov 24 | Syracuse, NY (Syracuse University- Waverly Ave. between Walnut Place and University Ave.) to Boston, MA (Dalton Street, Back Bay - Dalton and Belvidere Streets, East side of Dalton, across from Hilton hotel. One block to Prudential T station, 2 blocks to Hynes Convention Center T station) | OurBus Full timetable |
| 11:42 AM | 8:24 PM | 8h 42m | Daily | Syracuse Regional Transportation Center to Boston | Amtrak Full timetable |
| 12:00 PM | 6:25 PM | 6h 25m | Daily | Syracuse Bus Station to Boston South Station | Greyhound Full timetable |
| 2:30 PM | 8:55 PM | 6h 25m | Mon, Fri, Sun | Syracuse, NY (Syracuse University- Waverly Ave. between Walnut Place and University Ave.) to Boston, MA (Dalton Street, Back Bay - Dalton and Belvidere Streets, East side of Dalton, across from Hilton hotel. One block to Prudential T station, 2 blocks to Hynes Convention Center T station) | OurBus Full timetable |
| 3:55 PM | 10:25 PM | 6h 30m | Tue, Fri, Sun | Syracuse Bus Station to Boston South Station | FlixBus Full timetable |
Route map
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Where to board in Syracuse Where you get off in Boston The route of the busiest trip
Where to board in Syracuse
Where buses and trains stop in Boston
Return trip: Boston to Syracuse
Questions
How long is the bus or train from Syracuse to Boston?
The fastest direct bus or train takes 6 hours 20 minutes; the typical trip is 6 hours 30 minutes.
What time is the first departure from Syracuse to Boston?
The earliest departure is at 6:50 AM (Daily) and the last at 3:55 PM (Tue, Fri, Sun).
Which bus and rail companies go from Syracuse to Boston?
Amtrak, FlixBus, Greyhound and OurBus run direct buses and trains on this route.
Where do I board in Syracuse?
Buses and trains to Boston leave from Syracuse Regional Transportation Center and Syracuse (Syr Univ).
Does the bus or train from Syracuse to Boston stop at Syracuse Hancock International Airport?
Yes, 2 of the 26 a week: at Syracuse Airport (SYR Airport Terminal A).