MO → KY · about 140 miles
St. Louis to Paducah bus schedule
FlixBus runs 5 direct buses a week from St. Louis to Paducah. The fastest takes 3 hours 10 minutes; every bus leaves at 11:45 PM.
Timetable data from · No schedule changes since at least
- Buses a week
- 5
- Fastest trip
- 3h 10m
- Leaves at
- 11:45 PM
Timetable
Every bus leaves from St Louis Bus Station and arrives at Paducah KY (PAD). Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Bus company |
|---|---|---|---|---|
| 11:45 PM | 2:55 AM +1 day | 3h 10m | Mon, Thu, Fri, Sat, Sun | FlixBus Full timetable |
Route map
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Where to board in St. Louis Where you get off in Paducah The route of the busiest trip
Where to catch the bus in St. Louis
- St Louis Bus Station Map of St Louis Bus Station (Google Maps)
Where the bus stops in Paducah
- Paducah KY (PAD) Map of Paducah KY (PAD) (Google Maps)
Return trip: Paducah to St. Louis
Questions
How long is the bus from St. Louis to Paducah?
The fastest direct bus takes 3 hours 10 minutes.
What time is the first bus from St. Louis to Paducah?
Every departure is at 11:45 PM (Mon, Thu, Fri, Sat, Sun).
Which bus companies go from St. Louis to Paducah?
FlixBus runs direct buses on this route.
Where do I catch the bus in St. Louis?
Buses to Paducah leave from St Louis Bus Station.