MO → MO · about 106 miles
St. Louis to Jefferson City bus & train schedule
Amtrak and Greyhound run 21 direct buses and trains a week from St. Louis to Jefferson City. The fastest takes 2 hours 25 minutes; the first departure leaves at 8:10 AM and the last at 3:11 PM.
Timetable data from · Schedule last changed
- Buses and trains a week
- 21
- Fastest trip
- 2h 25m
- First departure
- 8:10 AM
- Last departure
- 3:11 PM
Timetable
Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Stops | Company |
|---|---|---|---|---|---|
| 8:10 AM | 10:35 AM | 2h 25m | Daily | St. Louis to Jefferson City Amtrak Station | Amtrak Full timetable |
| 12:30 PM | 4:35 PM | 4h 05m | Daily | St Louis Bus Station to Jefferson City Conoco | Greyhound Full timetable |
| 3:11 PM | 5:36 PM | 2h 25m | Daily | St. Louis to Jefferson City Amtrak Station | Amtrak Full timetable |
Route map
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Where to board in St. Louis Where you get off in Jefferson City The route of the busiest trip
Where to board in St. Louis
- St Louis Bus Station Map of St Louis Bus Station (Google Maps)
Where buses and trains stop in Jefferson City
Return trip: Jefferson City to St. Louis
Questions
How long is the bus or train from St. Louis to Jefferson City?
The fastest direct bus or train takes 2 hours 25 minutes; the typical trip is 2 hours 25 minutes.
What time is the first departure from St. Louis to Jefferson City?
The earliest departure is at 8:10 AM (Daily) and the last at 3:11 PM (Daily).
Which bus and rail companies go from St. Louis to Jefferson City?
Amtrak and Greyhound run direct buses and trains on this route.
Where do I board in St. Louis?
Buses and trains to Jefferson City leave from St Louis Bus Station.