MO → CO · about 792 miles
St. Louis to Denver bus schedule
Greyhound runs 14 direct buses a week from St. Louis to Denver. The fastest takes 17 hours 15 minutes; the first bus leaves at 5:15 PM and the last at 11:45 PM.
Timetable data from · No schedule changes since at least
- Buses a week
- 14
- Fastest trip
- 17h 15m
- First bus
- 5:15 PM
- Last bus
- 11:45 PM
Timetable
Every bus leaves from St Louis Bus Station and arrives at Denver Union Station Bus Concourse. Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Bus company |
|---|---|---|---|---|
| 5:15 PM | 9:30 AM +1 day | 17h 15m | Daily | Greyhound Full timetable |
| 11:45 PM | 4:05 PM +1 day | 17h 20m | Daily | Greyhound Full timetable |
Route map
The map needs JavaScript.
Where to board in St. Louis Where you get off in Denver The route of the busiest trip
Where to catch the bus in St. Louis
- St Louis Bus Station Map of St Louis Bus Station (Google Maps)
Where the bus stops in Denver
Return trip: Denver to St. Louis
Questions
How long is the bus from St. Louis to Denver?
The fastest direct bus takes 17 hours 15 minutes.
What time is the first bus from St. Louis to Denver?
The earliest departure is at 5:15 PM (Daily) and the last at 11:45 PM (Daily).
Which bus companies go from St. Louis to Denver?
Greyhound runs direct buses on this route.
Where do I catch the bus in St. Louis?
Buses to Denver leave from St Louis Bus Station.