SC → NC · about 124 miles
Spartanburg to Winston-Salem bus schedule
Greyhound runs 14 direct buses a week from Spartanburg to Winston-Salem. The fastest takes 3 hours 20 minutes; the first bus leaves at 3:30 AM and the last at 11:05 AM.
Timetable data from · Schedule last changed
- Buses a week
- 14
- Fastest trip
- 3h 20m
- First bus
- 3:30 AM
- Last bus
- 11:05 AM
Timetable
Every bus leaves from Spartanburg and arrives at Winston-Salem NC - Clark Campbell Trans. Ctr. (WNS). Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Bus company |
|---|---|---|---|---|
| 3:30 AM | 6:50 AM | 3h 20m | Daily | Greyhound Full timetable |
| 11:05 AM | 2:35 PM | 3h 30m | Daily | Greyhound Full timetable |
Route map
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Where to board in Spartanburg Where you get off in Winston-Salem The route of the busiest trip
Where to catch the bus in Spartanburg
Where the bus stops in Winston-Salem
Return trip: Winston-Salem to Spartanburg
Questions
How long is the bus from Spartanburg to Winston-Salem?
The fastest direct bus takes 3 hours 20 minutes.
What time is the first bus from Spartanburg to Winston-Salem?
The earliest departure is at 3:30 AM (Daily) and the last at 11:05 AM (Daily).
Which bus companies go from Spartanburg to Winston-Salem?
Greyhound runs direct buses on this route.
Where do I catch the bus in Spartanburg?
Buses to Winston-Salem leave from Spartanburg bus stop.