NC → NC · about 78 miles
Durham to Winston-Salem bus schedule
Greyhound runs 21 direct buses a week from Durham to Winston-Salem. The fastest takes 1 hour 45 minutes; the first bus leaves at 4:55 AM and the last at 4:20 PM.
Timetable data from · Schedule last changed
- Buses a week
- 21
- Fastest trip
- 1h 45m
- First bus
- 4:55 AM
- Last bus
- 4:20 PM
Timetable
Every bus leaves from Durham W Pettigrew St Bus Station and arrives at Winston-Salem NC - Clark Campbell Trans. Ctr. (WNS). Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Bus company |
|---|---|---|---|---|
| 4:55 AM | 6:45 AM | 1h 50m | Daily | Greyhound Full timetable |
| 2:20 PM | 4:25 PM | 2h 05m | Daily | Greyhound Full timetable |
| 4:20 PM | 6:05 PM | 1h 45m | Daily | Greyhound Full timetable |
Route map
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Where to board in Durham Where you get off in Winston-Salem The route of the busiest trip
Where to catch the bus in Durham
Where the bus stops in Winston-Salem
Return trip: Winston-Salem to Durham
Questions
How long is the bus from Durham to Winston-Salem?
The fastest direct bus takes 1 hour 45 minutes; the typical trip is 1 hour 50 minutes.
What time is the first bus from Durham to Winston-Salem?
The earliest departure is at 4:55 AM (Daily) and the last at 4:20 PM (Daily).
Which bus companies go from Durham to Winston-Salem?
Greyhound runs direct buses on this route.
Where do I catch the bus in Durham?
Buses to Winston-Salem leave from Durham W Pettigrew St Bus Station.