SC → NC · about 189 miles
Spartanburg to Durham bus schedule
Greyhound runs 7 direct buses a week from Spartanburg to Durham. The fastest takes 5 hours 20 minutes; every bus leaves at 3:30 AM.
Timetable data from · Schedule last changed
- Buses a week
- 7
- Fastest trip
- 5h 20m
- Leaves at
- 3:30 AM
Timetable
Every bus leaves from Spartanburg and arrives at Durham W Pettigrew St Bus Station. Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Bus company |
|---|---|---|---|---|
| 3:30 AM | 8:50 AM | 5h 20m | Daily | Greyhound Full timetable |
Route map
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Where to board in Spartanburg Where you get off in Durham The route of the busiest trip
Where to catch the bus in Spartanburg
Where the bus stops in Durham
Return trip: Durham to Spartanburg
Questions
How long is the bus from Spartanburg to Durham?
The fastest direct bus takes 5 hours 20 minutes.
What time is the first bus from Spartanburg to Durham?
Every departure is at 3:30 AM (Daily).
Which bus companies go from Spartanburg to Durham?
Greyhound runs direct buses on this route.
Where do I catch the bus in Spartanburg?
Buses to Durham leave from Spartanburg bus stop.