ME → NH · about 48 miles
South Portland to Portsmouth bus schedule
FlixBus and Greyhound run 12 direct buses a week from South Portland to Portsmouth. The fastest takes 56 minutes; the first bus leaves at 1:45 PM and the last at 11:59 PM.
Timetable data from · No schedule changes since at least
- Buses a week
- 12
- Fastest trip
- 56m
- First bus
- 1:45 PM
- Last bus
- 11:59 PM
Timetable
Every bus leaves from City of Portland and arrives at Portsmouth Bus Stop. Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Bus company |
|---|---|---|---|---|
| 1:45 PM | 2:50 PM | 1h 05m | Daily | Greyhound Full timetable |
| 11:59 PM | 12:55 AM +1 day | 56m | Mon, Tue, Fri, Sat, Sun | FlixBus Full timetable |
Route map
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Where to board in South Portland Where you get off in Portsmouth The route of the busiest trip
Where to catch the bus in South Portland
- City of Portland Map of City of Portland (Google Maps)
Where the bus stops in Portsmouth
Return trip: Portsmouth to South Portland
Questions
How long is the bus from South Portland to Portsmouth?
The fastest direct bus takes 56 minutes.
What time is the first bus from South Portland to Portsmouth?
The earliest departure is at 1:45 PM (Daily) and the last at 11:59 PM (Mon, Tue, Fri, Sat, Sun).
Which bus companies go from South Portland to Portsmouth?
FlixBus and Greyhound run direct buses on this route.
Where do I catch the bus in South Portland?
Buses to Portsmouth leave from City of Portland.