ME → MA · about 98 miles
South Portland to Boston bus schedule
FlixBus and Greyhound run 12 direct buses a week from South Portland to Boston. The fastest takes 2 hours 1 minute; the first bus leaves at 1:45 PM and the last at 11:59 PM.
Timetable data from · No schedule changes since at least
- Buses a week
- 12
- Fastest trip
- 2h 01m
- First bus
- 1:45 PM
- Last bus
- 11:59 PM
Timetable
Every bus leaves from City of Portland and arrives at Boston South Station. Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Bus company |
|---|---|---|---|---|
| 1:45 PM | 4:15 PM | 2h 30m | Daily | Greyhound Full timetable |
| 11:59 PM | 2:00 AM +1 day | 2h 01m | Mon, Tue, Fri, Sat, Sun | FlixBus Full timetable |
Route map
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Where to board in South Portland Where you get off in Boston The route of the busiest trip
Where to catch the bus in South Portland
- City of Portland Map of City of Portland (Google Maps)
Where the bus stops in Boston
Return trip: Boston to South Portland
Questions
How long is the bus from South Portland to Boston?
The fastest direct bus takes 2 hours 1 minute.
What time is the first bus from South Portland to Boston?
The earliest departure is at 1:45 PM (Daily) and the last at 11:59 PM (Mon, Tue, Fri, Sat, Sun).
Which bus companies go from South Portland to Boston?
FlixBus and Greyhound run direct buses on this route.
Where do I catch the bus in South Portland?
Buses to Boston leave from City of Portland.