NH → ME · about 48 miles
Portsmouth to South Portland bus schedule
FlixBus and Greyhound run 12 direct buses a week from Portsmouth to South Portland. The fastest takes 55 minutes; the first bus leaves at 6:15 AM and the last at 7:50 PM.
Timetable data from · No schedule changes since at least
- Buses a week
- 12
- Fastest trip
- 55m
- First bus
- 6:15 AM
- Last bus
- 7:50 PM
Timetable
Every bus leaves from Portsmouth Bus Stop and arrives at City of Portland. Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Bus company |
|---|---|---|---|---|
| 6:15 AM | 7:10 AM | 55m | Mon, Tue, Fri, Sat, Sun | FlixBus Full timetable |
| 7:50 PM | 8:50 PM | 1h 00m | Daily | Greyhound Full timetable |
Route map
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Where to board in Portsmouth Where you get off in South Portland The route of the busiest trip
Where to catch the bus in Portsmouth
Where the bus stops in South Portland
- City of Portland Map of City of Portland (Google Maps)
Return trip: South Portland to Portsmouth
Questions
How long is the bus from Portsmouth to South Portland?
The fastest direct bus takes 55 minutes.
What time is the first bus from Portsmouth to South Portland?
The earliest departure is at 6:15 AM (Mon, Tue, Fri, Sat, Sun) and the last at 7:50 PM (Daily).
Which bus companies go from Portsmouth to South Portland?
FlixBus and Greyhound run direct buses on this route.
Where do I catch the bus in Portsmouth?
Buses to South Portland leave from Portsmouth Bus Stop.