TX → LA · about 391 miles
San Antonio to Lafayette bus & train schedule
Amtrak and FlixBus run 8 direct buses and trains a week from San Antonio to Lafayette. The fastest takes 7 hours 20 minutes; the first departure leaves at 6:25 AM and the last at 10:00 AM.
Timetable data from · No schedule changes since at least
- Buses and trains a week
- 8
- Fastest trip
- 7h 20m
- First departure
- 6:25 AM
- Last departure
- 10:00 AM
Timetable
Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Stops | Company |
|---|---|---|---|---|---|
| 6:25 AM | 5:12 PM | 10h 47m | Mon, Thu, Sat | San Antonio Amtrak Station to Lafayette Amtrak Station | Amtrak Full timetable |
| 10:00 AM | 5:20 PM | 7h 20m | Mon, Thu, Fri, Sat, Sun | San Antonio Bus Station to Lafayette La | FlixBus Full timetable |
Route map
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Where to board in San Antonio Where you get off in Lafayette The route of the busiest trip
Where to board in San Antonio
Where buses and trains stop in Lafayette
Return trip: Lafayette to San Antonio
Questions
How long is the bus or train from San Antonio to Lafayette?
The fastest direct bus or train takes 7 hours 20 minutes; the typical trip is 10 hours 47 minutes.
What time is the first departure from San Antonio to Lafayette?
The earliest departure is at 6:25 AM (Mon, Thu, Sat) and the last at 10:00 AM (Mon, Thu, Fri, Sat, Sun).
Which bus and rail companies go from San Antonio to Lafayette?
Amtrak and FlixBus run direct buses and trains on this route.
Where do I board in San Antonio?
Buses and trains to Lafayette leave from San Antonio Amtrak Station and San Antonio Bus Station.