AL → LA · about 237 miles
Mobile to Lafayette bus schedule
FlixBus and Greyhound run 41 direct buses a week from Mobile to Lafayette. The fastest takes 4 hours 35 minutes; the first bus leaves at 2:15 AM and the last at 10:30 PM.
Timetable data from · No schedule changes since at least
- Buses a week
- 41
- Fastest trip
- 4h 35m
- First bus
- 2:15 AM
- Last bus
- 10:30 PM
Timetable
Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Stops | Bus company |
|---|---|---|---|---|---|
| 2:15 AM | 6:55 AM | 4h 40m | Daily | Mobile AL (MOG) to Lafayette Transit System | Greyhound Full timetable |
| 2:30 AM | 9:05 AM | 6h 35m | Daily | Mobile AL (MOG) to Lafayette Transit System | Greyhound Full timetable |
| 5:55 AM | 12:20 PM | 6h 25m | Daily | Mobile AL (MOG) to Lafayette Transit System | Greyhound Full timetable |
| 1:55 PM | 9:15 PM | 7h 20m | Daily | Mobile AL (MOG) to Lafayette Transit System | Greyhound Full timetable |
| 8:15 PM | 1:25 AM +1 day | 5h 10m | Daily except Wed | Mobile AL (MOG) to Lafayette La | FlixBus Full timetable |
| 10:30 PM | 3:05 AM +1 day | 4h 35m | Daily | Mobile AL (MOG) to Lafayette Transit System | Greyhound Full timetable |
Route map
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Where to board in Mobile Where you get off in Lafayette The route of the busiest trip
Where to catch the bus in Mobile
Where the bus stops in Lafayette
Return trip: Lafayette to Mobile
Questions
How long is the bus from Mobile to Lafayette?
The fastest direct bus takes 4 hours 35 minutes; the typical trip is 6 hours 25 minutes.
What time is the first bus from Mobile to Lafayette?
The earliest departure is at 2:15 AM (Daily) and the last at 10:30 PM (Daily).
Which bus companies go from Mobile to Lafayette?
FlixBus and Greyhound run direct buses on this route.
Where do I catch the bus in Mobile?
Buses to Lafayette leave from Mobile AL (MOG).