MS → LA · about 187 miles
Biloxi to Lafayette bus schedule
FlixBus and Greyhound run 20 direct buses a week from Biloxi to Lafayette. The fastest takes 4 hours 10 minutes; the first bus leaves at 3:40 AM and the last at 9:15 PM.
Timetable data from · No schedule changes since at least
- Buses a week
- 20
- Fastest trip
- 4h 10m
- First bus
- 3:40 AM
- Last bus
- 9:15 PM
Timetable
Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Stops | Bus company |
|---|---|---|---|---|---|
| 3:40 AM | 9:05 AM | 5h 25m | Daily | Biloxi MS (BIG) to Lafayette Transit System | Greyhound Full timetable |
| 3:10 PM | 9:15 PM | 6h 05m | Daily | Biloxi MS (BIG) to Lafayette Transit System | Greyhound Full timetable |
| 9:15 PM | 1:25 AM +1 day | 4h 10m | Daily except Wed | Biloxi MS (BIG) to Lafayette La | FlixBus Full timetable |
Route map
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Where to board in Biloxi Where you get off in Lafayette The route of the busiest trip
Where to catch the bus in Biloxi
Where the bus stops in Lafayette
Return trip: Lafayette to Biloxi
Questions
How long is the bus from Biloxi to Lafayette?
The fastest direct bus takes 4 hours 10 minutes; the typical trip is 5 hours 25 minutes.
What time is the first bus from Biloxi to Lafayette?
The earliest departure is at 3:40 AM (Daily) and the last at 9:15 PM (Daily except Wed).
Which bus companies go from Biloxi to Lafayette?
FlixBus and Greyhound run direct buses on this route.
Where do I catch the bus in Biloxi?
Buses to Lafayette leave from Biloxi MS (BIG).