LA → TX · about 391 miles
Lafayette to San Antonio bus & train schedule
Amtrak and FlixBus run 8 direct buses and trains a week from Lafayette to San Antonio. The fastest takes 7 hours 20 minutes; the first departure leaves at 12:24 PM and the last at 3:25 PM.
Timetable data from · No schedule changes since at least
- Buses and trains a week
- 8
- Fastest trip
- 7h 20m
- First departure
- 12:24 PM
- Last departure
- 3:25 PM
Timetable
Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Stops | Company |
|---|---|---|---|---|---|
| 12:24 PM | 12:05 AM +1 day | 11h 41m | Mon, Wed, Sat | Lafayette Amtrak Station to San Antonio Amtrak Station | Amtrak Full timetable |
| 3:25 PM | 10:45 PM | 7h 20m | Mon, Tue, Fri, Sat, Sun | Lafayette La to San Antonio Bus Station | FlixBus Full timetable |
Route map
The map needs JavaScript.
Where to board in Lafayette Where you get off in San Antonio The route of the busiest trip
Where to board in Lafayette
Where buses and trains stop in San Antonio
Return trip: San Antonio to Lafayette
Questions
How long is the bus or train from Lafayette to San Antonio?
The fastest direct bus or train takes 7 hours 20 minutes; the typical trip is 11 hours 41 minutes.
What time is the first departure from Lafayette to San Antonio?
The earliest departure is at 12:24 PM (Mon, Wed, Sat) and the last at 3:25 PM (Mon, Tue, Fri, Sat, Sun).
Which bus and rail companies go from Lafayette to San Antonio?
Amtrak and FlixBus run direct buses and trains on this route.
Where do I board in Lafayette?
Buses and trains to San Antonio leave from Lafayette Amtrak Station and Lafayette FlixBus bus stop.