NY → NY · about 262 miles
Poughkeepsie to Buffalo train schedule
Amtrak runs 28 direct trains a week from Poughkeepsie to Buffalo. The fastest takes 6 hours 34 minutes; the first train leaves at 8:45 AM and the last at 5:10 PM.
Timetable data from · No schedule changes since at least
- Trains a week
- 28
- Fastest trip
- 6h 34m
- First train
- 8:45 AM
- Last train
- 5:10 PM
Timetable
Every train leaves from Poughkeepsie Amtrak Station and arrives at Buffalo Depew Station. Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Rail company |
|---|---|---|---|---|
| 8:45 AM | 3:19 PM | 6h 34m | Daily from Nov 2 | Amtrak Full timetable |
| 8:45 AM | 3:25 PM | 6h 40m | Daily | Amtrak Full timetable |
| 11:43 AM | 6:34 PM | 6h 51m | Daily from Nov 2 | Amtrak Full timetable |
| 11:43 AM | 6:40 PM | 6h 57m | Sat & Sun | Amtrak Full timetable |
| 11:48 AM | 6:40 PM | 6h 52m | Mon–Fri | Amtrak Full timetable |
| 2:45 PM | 9:21 PM | 6h 36m | Daily from Nov 2 | Amtrak Full timetable |
| 2:45 PM | 9:27 PM | 6h 42m | Sat & Sun | Amtrak Full timetable |
| 2:48 PM | 9:27 PM | 6h 39m | Mon–Fri | Amtrak Full timetable |
| 5:10 PM | 12:29 AM +1 day | 7h 19m | Daily | Amtrak Full timetable |
Route map
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Where to board in Poughkeepsie Where you get off in Buffalo The route of the busiest trip
Where to catch the train in Poughkeepsie
- Poughkeepsie Amtrak Station Map of Poughkeepsie Amtrak Station (Google Maps)
Where the train stops in Buffalo
Return trip: Buffalo to Poughkeepsie
Questions
How long is the train from Poughkeepsie to Buffalo?
The fastest direct train takes 6 hours 34 minutes; the typical trip is 6 hours 51 minutes.
What time is the first train from Poughkeepsie to Buffalo?
The earliest departure is at 8:45 AM (Daily) and the last at 5:10 PM (Daily).
Which rail companies go from Poughkeepsie to Buffalo?
Amtrak runs direct trains on this route.
Where do I catch the train in Poughkeepsie?
Trains to Buffalo leave from Poughkeepsie Amtrak Station.