FL → SC · about 345 miles
Orlando to Orangeburg bus schedule
FlixBus runs 7 direct buses a week from Orlando to Orangeburg. The fastest takes 7 hours 20 minutes; every bus leaves at 2:30 PM.
Timetable data from · No schedule changes since at least
- Buses a week
- 7
- Fastest trip
- 7h 20m
- Leaves at
- 2:30 PM
Timetable
Every bus leaves from Orlando Bus Station and arrives at Orangeburg (Xpress Travel Center). Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Bus company |
|---|---|---|---|---|
| 2:30 PM | 9:50 PM | 7h 20m | Daily | FlixBus Full timetable |
Route map
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Where to board in Orlando Where you get off in Orangeburg The route of the busiest trip
Where to catch the bus in Orlando
Where the bus stops in Orangeburg
- Orangeburg (Xpress Travel Center) Map of Orangeburg (Xpress Travel Center) (Google Maps)
Return trip: Orangeburg to Orlando
Questions
How long is the bus from Orlando to Orangeburg?
The fastest direct bus takes 7 hours 20 minutes.
What time is the first bus from Orlando to Orangeburg?
Every departure is at 2:30 PM (Daily).
Which bus companies go from Orlando to Orangeburg?
FlixBus runs direct buses on this route.
Where do I catch the bus in Orlando?
Buses to Orangeburg leave from Orlando Bus Station.