AL → LA · about 426 miles
Opelika to Lafayette bus schedule
Greyhound runs 14 direct buses a week from Opelika to Lafayette. The fastest takes 11 hours 25 minutes; the first bus leaves at 9:05 AM and the last at 9:40 PM.
Timetable data from · No schedule changes since at least
- Buses a week
- 14
- Fastest trip
- 11h 25m
- First bus
- 9:05 AM
- Last bus
- 9:40 PM
Timetable
Every bus leaves from Opelika 4Th Street Station and arrives at Lafayette Transit System. Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Bus company |
|---|---|---|---|---|
| 9:05 AM | 9:15 PM | 12h 10m | Daily | Greyhound Full timetable |
| 9:40 PM | 9:05 AM +1 day | 11h 25m | Daily | Greyhound Full timetable |
Route map
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Where to board in Opelika Where you get off in Lafayette The route of the busiest trip
Where to catch the bus in Opelika
- Opelika 4Th Street Station Map of Opelika 4Th Street Station (Google Maps)
Where the bus stops in Lafayette
Questions
How long is the bus from Opelika to Lafayette?
The fastest direct bus takes 11 hours 25 minutes.
What time is the first bus from Opelika to Lafayette?
The earliest departure is at 9:05 AM (Daily) and the last at 9:40 PM (Daily).
Which bus companies go from Opelika to Lafayette?
Greyhound runs direct buses on this route.
Where do I catch the bus in Opelika?
Buses to Lafayette leave from Opelika 4Th Street Station.