NY → NY · about 147 miles
Niagara Falls to Syracuse bus & train schedule
Amtrak, FlixBus and OurBus run 39 direct buses and trains a week from Niagara Falls to Syracuse. The fastest takes 2 hours 54 minutes; the first departure leaves at 3:42 AM and the last at 9:20 PM.
Timetable data from · Schedule last changed
- Buses and trains a week
- 39
- Fastest trip
- 2h 54m
- First departure
- 3:42 AM
- Last departure
- 9:20 PM
Timetable
Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Stops | Company |
|---|---|---|---|---|---|
| 3:42 AM | 6:53 AM | 3h 11m | Daily | Niagara Falls Amtrak Station to Syracuse Regional Transportation Center | Amtrak Full timetable |
| 3:52 AM | 6:57 AM | 3h 05m | Daily from Nov 2 | Niagara Falls Amtrak Station to Syracuse Regional Transportation Center | Amtrak Full timetable |
| 4:50 AM | 8:25 AM | 3h 35m | Mon, Tue, Fri, Sat, Sun | Niagara Falls Old Main St to Syracuse Bus Station | FlixBus Full timetable |
| 6:37 AM | 9:45 AM | 3h 08m | Daily | Niagara Falls Amtrak Station to Syracuse Regional Transportation Center | Amtrak Full timetable |
| 6:47 AM | 9:49 AM | 3h 02m | Daily from Nov 2 | Niagara Falls Amtrak Station to Syracuse Regional Transportation Center | Amtrak Full timetable |
| 8:20 AM | 12:05 PM | 3h 45m | Daily | Niagara Falls Old Main St to Syracuse Bus Station | FlixBus Full timetable |
| 11:40 AM | 2:40 PM | 3h 00m | Tue–Sun | Niagara Falls Amtrak Station to Syracuse Regional Transportation Center | Amtrak Full timetable |
| 11:50 AM | 2:44 PM | 2h 54m | Daily from Nov 2 | Niagara Falls Amtrak Station to Syracuse Regional Transportation Center | Amtrak Full timetable |
| 2:00 PM | 5:40 PM | 3h 40m | Daily from Nov 19 | Niagara Falls, NY (Old Main Street, charter bus zone behind visitor center. One block from Niagara Falls State Park) to Syracuse, NY (Syracuse University- Waverly Ave. between Walnut Place and University Ave.) | OurBus Full timetable |
| 9:20 PM | 1:05 AM +1 day | 3h 45m | Daily | Niagara Falls Old Main St to Syracuse Bus Station | FlixBus Full timetable |
Route map
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Where to board in Niagara Falls Where you get off in Syracuse The route of the busiest trip
Where to board in Niagara Falls
Where buses and trains stop in Syracuse
Return trip: Syracuse to Niagara Falls
Questions
How long is the bus or train from Niagara Falls to Syracuse?
The fastest direct bus or train takes 2 hours 54 minutes; the typical trip is 3 hours 11 minutes.
What time is the first departure from Niagara Falls to Syracuse?
The earliest departure is at 3:42 AM (Daily) and the last at 9:20 PM (Daily).
Which bus and rail companies go from Niagara Falls to Syracuse?
Amtrak, FlixBus and OurBus run direct buses and trains on this route.
Where do I board in Niagara Falls?
Buses and trains to Syracuse leave from Niagara Falls Amtrak Station and Niagara Falls Old Main St.