NE → IL · about 631 miles
Lexington to Chicago bus schedule
Greyhound runs 7 direct buses a week from Lexington to Chicago. The fastest takes 15 hours 5 minutes; every bus leaves at 1:20 AM.
Timetable data from · No schedule changes since at least
- Buses a week
- 7
- Fastest trip
- 15h 05m
- Leaves at
- 1:20 AM
Timetable
Every bus leaves from Lexington Phillips 66 and arrives at Chicago Bus Station. Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Bus company |
|---|---|---|---|---|
| 1:20 AM | 4:25 PM | 15h 05m | Daily | Greyhound Full timetable |
Route map
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Where to board in Lexington Where you get off in Chicago The route of the busiest trip
Where to catch the bus in Lexington
- Lexington Phillips 66 Map of Lexington Phillips 66 (Google Maps)
Where the bus stops in Chicago
Return trip: Chicago to Lexington
Questions
How long is the bus from Lexington to Chicago?
The fastest direct bus takes 15 hours 5 minutes.
What time is the first bus from Lexington to Chicago?
Every departure is at 1:20 AM (Daily).
Which bus companies go from Lexington to Chicago?
Greyhound runs direct buses on this route.
Where do I catch the bus in Lexington?
Buses to Chicago leave from Lexington Phillips 66.