TN → VA · about 234 miles
Knoxville to Roanoke bus schedule
Greyhound runs 7 direct buses a week from Knoxville to Roanoke. The fastest takes 4 hours; every bus leaves at 10:40 PM.
Timetable data from · No schedule changes since at least
- Buses a week
- 7
- Fastest trip
- 4h 00m
- Leaves at
- 10:40 PM
Timetable
Every bus leaves from Knoxville Area Transit Bus Stop and arrives at Roanoke Bus Stop. Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Bus company |
|---|---|---|---|---|
| 10:40 PM | 3:40 AM +1 day | 4h 00m | Daily | Greyhound Full timetable |
Route map
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Where to board in Knoxville Where you get off in Roanoke The route of the busiest trip
Where to catch the bus in Knoxville
- Knoxville Area Transit Bus Stop Map of Knoxville Area Transit Bus Stop (Google Maps)
Where the bus stops in Roanoke
Questions
How long is the bus from Knoxville to Roanoke?
The fastest direct bus takes 4 hours.
What time is the first bus from Knoxville to Roanoke?
Every departure is at 10:40 PM (Daily).
Which bus companies go from Knoxville to Roanoke?
Greyhound runs direct buses on this route.
Where do I catch the bus in Knoxville?
Buses to Roanoke leave from Knoxville Area Transit Bus Stop.