TN → OH · about 220 miles
Knoxville to Cincinnati bus schedule
Greyhound runs 7 direct buses a week from Knoxville to Cincinnati. The fastest takes 4 hours 40 minutes; every bus leaves at 10:00 PM.
Timetable data from · No schedule changes since at least
- Buses a week
- 7
- Fastest trip
- 4h 40m
- Leaves at
- 10:00 PM
Timetable
Every bus leaves from Knoxville Area Transit Bus Stop and arrives at Cincinnati Bus Station. Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Bus company |
|---|---|---|---|---|
| 10:00 PM | 3:40 AM +1 day | 4h 40m | Daily | Greyhound Full timetable |
Route map
The map needs JavaScript.
Where to board in Knoxville Where you get off in Cincinnati The route of the busiest trip
Where to catch the bus in Knoxville
- Knoxville Area Transit Bus Stop Map of Knoxville Area Transit Bus Stop (Google Maps)
Where the bus stops in Cincinnati
Questions
How long is the bus from Knoxville to Cincinnati?
The fastest direct bus takes 4 hours 40 minutes.
What time is the first bus from Knoxville to Cincinnati?
Every departure is at 10:00 PM (Daily).
Which bus companies go from Knoxville to Cincinnati?
Greyhound runs direct buses on this route.
Where do I catch the bus in Knoxville?
Buses to Cincinnati leave from Knoxville Area Transit Bus Stop.