MD → VA · about 227 miles
Baltimore to Roanoke bus & train schedule
Amtrak and FlixBus run 17 direct buses and trains a week from Baltimore to Roanoke. The fastest takes 6 hours 22 minutes; the first departure leaves at 6:10 AM and the last at 3:42 PM.
Timetable data from · Schedule last changed
- Buses and trains a week
- 17
- Fastest trip
- 6h 22m
- First departure
- 6:10 AM
- Last departure
- 3:42 PM
Timetable
Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Stops | Company |
|---|---|---|---|---|---|
| 6:10 AM | 12:40 PM | 6h 30m | Daily from Dec 19 | Baltimore Penn Station to Roanoke | Amtrak Full timetable |
| 6:16 AM | 12:40 PM | 6h 24m | Daily | Baltimore Penn Station to Roanoke | Amtrak Full timetable |
| 6:18 AM | 12:40 PM | 6h 22m | Mon–Fri | Baltimore Penn Station to Roanoke | Amtrak Full timetable |
| 9:05 AM | 5:10 PM | 8h 05m | Mon, Fri, Sat, Sun | Baltimore Downtown Bus Station to Roanoke Orange Avenue Northeast | FlixBus Full timetable |
| 3:30 PM | 10:06 PM | 6h 36m | Daily | Baltimore Penn Station to Roanoke | Amtrak Full timetable |
| 3:33 PM | 10:13 PM | 6h 40m | Mon–Thu from Dec 21 | Baltimore Penn Station to Roanoke | Amtrak Full timetable |
| 3:34 PM | 10:06 PM | 6h 32m | Sat & Sun from Nov 28 | Baltimore Penn Station to Roanoke | Amtrak Full timetable |
| 3:36 PM | 10:06 PM | 6h 30m | Sat from Dec 19 | Baltimore Penn Station to Roanoke | Amtrak Full timetable |
| 3:36 PM | 10:13 PM | 6h 37m | Mon–Fri from Nov 16 | Baltimore Penn Station to Roanoke | Amtrak Full timetable |
| 3:37 PM | 10:06 PM | 6h 29m | Sun from Nov 22 | Baltimore Penn Station to Roanoke | Amtrak Full timetable |
| 3:42 PM | 10:06 PM | 6h 24m | Thu, Sat from Nov 21 | Baltimore Penn Station to Roanoke | Amtrak Full timetable |
Route map
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Where to board in Baltimore Where you get off in Roanoke The route of the busiest trip
Where to board in Baltimore
Where buses and trains stop in Roanoke
Return trip: Roanoke to Baltimore
Questions
How long is the bus or train from Baltimore to Roanoke?
The fastest direct bus or train takes 6 hours 22 minutes; the typical trip is 6 hours 32 minutes.
What time is the first departure from Baltimore to Roanoke?
The earliest departure is at 6:10 AM (Daily) and the last at 3:42 PM (Sat).
Which bus and rail companies go from Baltimore to Roanoke?
Amtrak and FlixBus run direct buses and trains on this route.
Where do I board in Baltimore?
Buses and trains to Roanoke leave from Baltimore Penn Station and Baltimore (Downtown).