MA → NY · about 379 miles
Framingham to Buffalo train schedule
Amtrak runs 7 direct trains a week from Framingham to Buffalo. The fastest takes 11 hours 4 minutes; every train leaves at 1:25 PM.
Timetable data from · No schedule changes since at least
- Trains a week
- 7
- Fastest trip
- 11h 04m
- Leaves at
- 1:25 PM
Timetable
Every train leaves from Framingham Amtrak and arrives at Buffalo Depew Station. Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Rail company |
|---|---|---|---|---|
| 1:25 PM | 12:29 AM +1 day | 11h 04m | Daily | Amtrak Full timetable |
Route map
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Where to board in Framingham Where you get off in Buffalo The route of the busiest trip
Where to catch the train in Framingham
Where the train stops in Buffalo
Return trip: Buffalo to Framingham
Questions
How long is the train from Framingham to Buffalo?
The fastest direct train takes 11 hours 4 minutes; the typical trip is 11 hours 4 minutes.
What time is the first train from Framingham to Buffalo?
Every departure is at 1:25 PM (Daily).
Which rail companies go from Framingham to Buffalo?
Amtrak runs direct trains on this route.
Where do I catch the train in Framingham?
Trains to Buffalo leave from Framingham Amtrak.