NC → MD · about 259 miles
Durham to Baltimore bus & train schedule
Amtrak, FlixBus and Greyhound run 21 direct buses and trains a week from Durham to Baltimore. The fastest takes 6 hours 25 minutes; the first departure leaves at 2:15 AM and the last at 9:27 AM.
Timetable data from · Schedule last changed
- Buses and trains a week
- 21
- Fastest trip
- 6h 25m
- First departure
- 2:15 AM
- Last departure
- 9:27 AM
Timetable
Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Stops | Company |
|---|---|---|---|---|---|
| 2:15 AM | 8:40 AM | 6h 25m | Daily | Durham W Pettigrew St Bus Station to Baltimore Downtown Bus Station | FlixBus Full timetable |
| 9:00 AM | 5:45 PM | 8h 45m | Daily | Durham W Pettigrew St Bus Station to Baltimore Downtown Bus Station | Greyhound Full timetable |
| 9:27 AM | 5:42 PM | 8h 15m | Sat & Sun from Nov 7 | Durham Amtrak Station to Baltimore Penn Station | Amtrak Full timetable |
| 9:27 AM | 5:47 PM | 8h 20m | Daily | Durham Amtrak Station to Baltimore Penn Station | Amtrak Full timetable |
Route map
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Where to board in Durham Where you get off in Baltimore The route of the busiest trip
Where to board in Durham
Where buses and trains stop in Baltimore
Return trip: Baltimore to Durham
Questions
How long is the bus or train from Durham to Baltimore?
The fastest direct bus or train takes 6 hours 25 minutes; the typical trip is 8 hours 20 minutes.
What time is the first departure from Durham to Baltimore?
The earliest departure is at 2:15 AM (Daily) and the last at 9:27 AM (Daily).
Which bus and rail companies go from Durham to Baltimore?
Amtrak, FlixBus and Greyhound run direct buses and trains on this route.
Where do I board in Durham?
Buses and trains to Baltimore leave from Durham Amtrak Station and Durham W Pettigrew St Bus Station.