MD → NC · about 259 miles
Baltimore to Durham bus & train schedule
Amtrak, FlixBus and Greyhound run 35 direct buses and trains a week from Baltimore to Durham. The fastest takes 6 hours 50 minutes; the first departure leaves at 1:35 AM and the last at 8:55 PM.
Timetable data from · Schedule last changed
- Buses and trains a week
- 35
- Fastest trip
- 6h 50m
- First departure
- 1:35 AM
- Last departure
- 8:55 PM
Timetable
Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Stops | Company |
|---|---|---|---|---|---|
| 1:35 AM | 8:25 AM | 6h 50m | Daily | Baltimore Downtown Bus Station to Durham W Pettigrew St Bus Station | FlixBus Full timetable |
| 7:05 AM | 4:10 PM | 9h 05m | Daily | Baltimore Downtown Bus Station to Durham W Pettigrew St Bus Station | Greyhound Full timetable |
| 10:13 AM | 7:55 PM | 9h 42m | Daily | Baltimore Penn Station to Durham Amtrak Station | Amtrak Full timetable |
| 5:00 PM | 1:30 AM +1 day | 8h 30m | Daily | Baltimore Downtown Bus Station to Durham W Pettigrew St Bus Station | Greyhound Full timetable |
| 8:55 PM | 4:50 AM +1 day | 7h 55m | Daily | Baltimore Downtown Bus Station to Durham W Pettigrew St Bus Station | Greyhound Full timetable |
Route map
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Where to board in Baltimore Where you get off in Durham The route of the busiest trip
Where to board in Baltimore
Where buses and trains stop in Durham
Return trip: Durham to Baltimore
Questions
How long is the bus or train from Baltimore to Durham?
The fastest direct bus or train takes 6 hours 50 minutes; the typical trip is 9 hours 5 minutes.
What time is the first departure from Baltimore to Durham?
The earliest departure is at 1:35 AM (Daily) and the last at 8:55 PM (Daily).
Which bus and rail companies go from Baltimore to Durham?
Amtrak, FlixBus and Greyhound run direct buses and trains on this route.
Where do I board in Baltimore?
Buses and trains to Durham leave from Baltimore Penn Station and Baltimore (Downtown).