OH → PA · about 326 miles
Columbus to Harrisburg bus schedule
Greyhound runs 21 direct buses a week from Columbus to Harrisburg. The fastest takes 8 hours 50 minutes; the first bus leaves at 12:50 AM and the last at 8:45 PM.
Timetable data from · No schedule changes since at least
- Buses a week
- 21
- Fastest trip
- 8h 50m
- First bus
- 12:50 AM
- Last bus
- 8:45 PM
Timetable
Every bus leaves from Columbus E Mound St and arrives at Harrisburg Market St Train Station. Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Bus company |
|---|---|---|---|---|
| 12:50 AM | 10:25 AM | 9h 35m | Daily | Greyhound Full timetable |
| 2:00 PM | 11:15 PM | 9h 15m | Daily | Greyhound Full timetable |
| 8:45 PM | 5:35 AM +1 day | 8h 50m | Daily | Greyhound Full timetable |
Route map
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Where to board in Columbus Where you get off in Harrisburg The route of the busiest trip
Where to catch the bus in Columbus
Where the bus stops in Harrisburg
Return trip: Harrisburg to Columbus
Questions
How long is the bus from Columbus to Harrisburg?
The fastest direct bus takes 8 hours 50 minutes; the typical trip is 9 hours 15 minutes.
What time is the first bus from Columbus to Harrisburg?
The earliest departure is at 12:50 AM (Daily) and the last at 8:45 PM (Daily).
Which bus companies go from Columbus to Harrisburg?
Greyhound runs direct buses on this route.
Where do I catch the bus in Columbus?
Buses to Harrisburg leave from Columbus (E Mound St).