PA → OH · about 326 miles
Harrisburg to Columbus bus schedule
Greyhound runs 14 direct buses a week from Harrisburg to Columbus. The fastest takes 8 hours 45 minutes; the first bus leaves at 2:50 PM and the last at 7:50 PM.
Timetable data from · No schedule changes since at least
- Buses a week
- 14
- Fastest trip
- 8h 45m
- First bus
- 2:50 PM
- Last bus
- 7:50 PM
Timetable
Every bus leaves from Harrisburg Market St Train Station and arrives at Columbus E Mound St. Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Bus company |
|---|---|---|---|---|
| 2:50 PM | 11:45 PM | 8h 55m | Daily | Greyhound Full timetable |
| 7:50 PM | 4:35 AM +1 day | 8h 45m | Daily | Greyhound Full timetable |
Route map
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Where to board in Harrisburg Where you get off in Columbus The route of the busiest trip
Where to catch the bus in Harrisburg
Where the bus stops in Columbus
Return trip: Columbus to Harrisburg
Questions
How long is the bus from Harrisburg to Columbus?
The fastest direct bus takes 8 hours 45 minutes.
What time is the first bus from Harrisburg to Columbus?
The earliest departure is at 2:50 PM (Daily) and the last at 7:50 PM (Daily).
Which bus companies go from Harrisburg to Columbus?
Greyhound runs direct buses on this route.
Where do I catch the bus in Harrisburg?
Buses to Columbus leave from Harrisburg Market St Train Station.