OH → IN · about 155 miles
Cincinnati to Lafayette bus & train schedule
Amtrak and FlixBus run 11 direct buses and trains a week from Cincinnati to Lafayette. The fastest takes 3 hours 35 minutes; the first departure leaves at 2:21 AM and the last at 1:40 PM.
Timetable data from · Schedule last changed
- Buses and trains a week
- 11
- Fastest trip
- 3h 35m
- First departure
- 2:21 AM
- Last departure
- 1:40 PM
Timetable
Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Stops | Company |
|---|---|---|---|---|---|
| 2:21 AM | 8:01 AM | 5h 40m | Mon, Thu, Sat | Cincinnati Union Terminal to Lafayette Amtrak Station | Amtrak Full timetable |
| 7:00 AM | 10:40 AM | 3h 40m | Daily except Tue | Cincinnati Cincinnati University of Cincinnati to Lafayette North 3rd Street | FlixBus Full timetable |
| 1:40 PM | 5:15 PM | 3h 35m | Thu, Fri | Cincinnati Cincinnati University of Cincinnati to Lafayette North 3rd Street | FlixBus Full timetable |
Route map
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Where to board in Cincinnati Where you get off in Lafayette The route of the busiest trip
Where to board in Cincinnati
Where buses and trains stop in Lafayette
Return trip: Lafayette to Cincinnati
Questions
How long is the bus or train from Cincinnati to Lafayette?
The fastest direct bus or train takes 3 hours 35 minutes; the typical trip is 5 hours 40 minutes.
What time is the first departure from Cincinnati to Lafayette?
The earliest departure is at 2:21 AM (Mon, Thu, Sat) and the last at 1:40 PM (Thu, Fri).
Which bus and rail companies go from Cincinnati to Lafayette?
Amtrak and FlixBus run direct buses and trains on this route.
Where do I board in Cincinnati?
Buses and trains to Lafayette leave from Cincinnati Union Terminal and Cincinnati (Univ Of Cin).