IL → OH · about 251 miles
Chicago to Cincinnati bus & train schedule
Amtrak and FlixBus run 14 direct buses and trains a week from Chicago to Cincinnati. The fastest takes 5 hours 35 minutes; the first departure leaves at 7:00 AM and the last at 5:55 PM.
Timetable data from · No schedule changes since at least
- Buses and trains a week
- 14
- Fastest trip
- 5h 35m
- First departure
- 7:00 AM
- Last departure
- 5:55 PM
Timetable
Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Stops | Company |
|---|---|---|---|---|---|
| 7:00 AM | 2:05 PM | 6h 05m | Mon, Tue, Fri, Sat, Sun | Chicago Bus Station to Cincinnati (Downtown) | FlixBus Full timetable |
| 10:30 AM | 5:05 PM | 5h 35m | Daily except Wed | Chicago Bus Station to Cincinnati (Downtown) | FlixBus Full timetable |
| 5:55 PM | 3:27 AM +1 day | 8h 32m | Tue, Thu, Sat | Chicago Union Station to Cincinnati Union Terminal | Amtrak Full timetable |
Route map
The map needs JavaScript.
Where to board in Chicago Where you get off in Cincinnati The route of the busiest trip
Where to board in Chicago
Where buses and trains stop in Cincinnati
Return trip: Cincinnati to Chicago
Questions
How long is the bus or train from Chicago to Cincinnati?
The fastest direct bus or train takes 5 hours 35 minutes; the typical trip is 8 hours 32 minutes.
What time is the first departure from Chicago to Cincinnati?
The earliest departure is at 7:00 AM (Mon, Fri, Sat, Sun) and the last at 5:55 PM (Tue, Thu, Sat).
Which bus and rail companies go from Chicago to Cincinnati?
Amtrak and FlixBus run direct buses and trains on this route.
Where do I board in Chicago?
Buses and trains to Cincinnati leave from Chicago Union Station and Chicago Bus Station.