MD → IL · about 606 miles
Baltimore to Chicago bus & train schedule
Amtrak and Greyhound run 10 direct buses and trains a week from Baltimore to Chicago. The fastest takes 20 hours 30 minutes; the first departure leaves at 12:35 AM and the last at 9:38 AM.
Timetable data from · Schedule last changed
- Buses and trains a week
- 10
- Fastest trip
- 20h 30m
- First departure
- 12:35 AM
- Last departure
- 9:38 AM
Timetable
Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Stops | Company |
|---|---|---|---|---|---|
| 12:35 AM | 8:05 PM | 20h 30m | Daily | Baltimore Downtown Bus Station to Chicago Bus Station | Greyhound Full timetable |
| 9:33 AM | 10:25 AM +1 day | 25h 52m | Wed, Fri, Sun from Dec 20 | Baltimore Penn Station to Chicago Union Station | Amtrak Full timetable |
| 9:38 AM | 10:25 AM +1 day | 25h 47m | Wed, Fri, Sun | Baltimore Penn Station to Chicago Union Station | Amtrak Full timetable |
Route map
The map needs JavaScript.
Where to board in Baltimore Where you get off in Chicago The route of the busiest trip
Where to board in Baltimore
Where buses and trains stop in Chicago
Return trip: Chicago to Baltimore
Questions
How long is the bus or train from Baltimore to Chicago?
The fastest direct bus or train takes 20 hours 30 minutes; the typical trip is 25 hours 47 minutes.
What time is the first departure from Baltimore to Chicago?
The earliest departure is at 12:35 AM (Daily) and the last at 9:38 AM (Wed, Fri, Sun).
Which bus and rail companies go from Baltimore to Chicago?
Amtrak and Greyhound run direct buses and trains on this route.
Where do I board in Baltimore?
Buses and trains to Chicago leave from Baltimore Penn Station and Baltimore (Downtown).