MO → OH · about 358 miles
St. Louis to Springfield bus schedule
Greyhound runs 21 direct buses a week from St. Louis to Springfield. The fastest takes 7 hours 45 minutes; the first bus leaves at 2:00 AM and the last at 2:05 PM.
Timetable data from · No schedule changes since at least
- Buses a week
- 21
- Fastest trip
- 7h 45m
- First bus
- 2:00 AM
- Last bus
- 2:05 PM
Timetable
Every bus leaves from St Louis Bus Station and arrives at Springfield Love'S. Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Bus company |
|---|---|---|---|---|
| 2:00 AM | 11:59 AM | 8h 59m | Daily | Greyhound Full timetable |
| 8:45 AM | 6:50 PM | 9h 05m | Daily | Greyhound Full timetable |
| 2:05 PM | 10:50 PM | 7h 45m | Daily | Greyhound Full timetable |
Route map
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Where to board in St. Louis Where you get off in Springfield The route of the busiest trip
Where to catch the bus in St. Louis
- St Louis Bus Station Map of St Louis Bus Station (Google Maps)
Where the bus stops in Springfield
- Springfield Love'S Map of Springfield Love'S (Google Maps)
Return trip: Springfield to St. Louis
Questions
How long is the bus from St. Louis to Springfield?
The fastest direct bus takes 7 hours 45 minutes; the typical trip is 8 hours 59 minutes.
What time is the first bus from St. Louis to Springfield?
The earliest departure is at 2:00 AM (Daily) and the last at 2:05 PM (Daily).
Which bus companies go from St. Louis to Springfield?
Greyhound runs direct buses on this route.
Where do I catch the bus in St. Louis?
Buses to Springfield leave from St Louis Bus Station.