MO → TN · about 254 miles
St. Louis to Nashville bus schedule
FlixBus and Greyhound run 19 direct buses a week from St. Louis to Nashville. The fastest takes 5 hours 50 minutes; the first bus leaves at 9:00 AM and the last at 11:45 PM.
Timetable data from · No schedule changes since at least
- Buses a week
- 19
- Fastest trip
- 5h 50m
- First bus
- 9:00 AM
- Last bus
- 11:45 PM
Timetable
Every bus leaves from St Louis Bus Station and arrives at Nashville TN (NVL). Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Bus company |
|---|---|---|---|---|
| 9:00 AM | 3:35 PM | 6h 35m | Daily | Greyhound Full timetable |
| 1:45 PM | 8:50 PM | 7h 05m | Daily | Greyhound Full timetable |
| 11:45 PM | 5:35 AM +1 day | 5h 50m | Mon, Thu, Fri, Sat, Sun | FlixBus Full timetable |
Route map
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Where to board in St. Louis Where you get off in Nashville The route of the busiest trip
Where to catch the bus in St. Louis
- St Louis Bus Station Map of St Louis Bus Station (Google Maps)
Where the bus stops in Nashville
- Nashville TN (NVL) Map of Nashville TN (NVL) (Google Maps)
Return trip: Nashville to St. Louis
Questions
How long is the bus from St. Louis to Nashville?
The fastest direct bus takes 5 hours 50 minutes; the typical trip is 6 hours 35 minutes.
What time is the first bus from St. Louis to Nashville?
The earliest departure is at 9:00 AM (Daily) and the last at 11:45 PM (Mon, Thu, Fri, Sat, Sun).
Which bus companies go from St. Louis to Nashville?
FlixBus and Greyhound run direct buses on this route.
Where do I catch the bus in St. Louis?
Buses to Nashville leave from St Louis Bus Station.