MO → IL · about 95 miles
St. Louis to Effingham bus schedule
Greyhound runs 14 direct buses a week from St. Louis to Effingham. The fastest takes 1 hour 45 minutes; the first bus leaves at 8:45 AM and the last at 2:05 PM.
Timetable data from · No schedule changes since at least
- Buses a week
- 14
- Fastest trip
- 1h 45m
- First bus
- 8:45 AM
- Last bus
- 2:05 PM
Timetable
Every bus leaves from St Louis Bus Station and arrives at Effingham W Fayette Ave. Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Bus company |
|---|---|---|---|---|
| 8:45 AM | 10:30 AM | 1h 45m | Daily | Greyhound Full timetable |
| 2:05 PM | 3:50 PM | 1h 45m | Daily | Greyhound Full timetable |
Route map
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Where to board in St. Louis Where you get off in Effingham The route of the busiest trip
Where to catch the bus in St. Louis
- St Louis Bus Station Map of St Louis Bus Station (Google Maps)
Where the bus stops in Effingham
Return trip: Effingham to St. Louis
Questions
How long is the bus from St. Louis to Effingham?
The fastest direct bus takes 1 hour 45 minutes.
What time is the first bus from St. Louis to Effingham?
The earliest departure is at 8:45 AM (Daily) and the last at 2:05 PM (Daily).
Which bus companies go from St. Louis to Effingham?
Greyhound runs direct buses on this route.
Where do I catch the bus in St. Louis?
Buses to Effingham leave from St Louis Bus Station.