SC → NC · about 121 miles
Orangeburg to Charlotte bus schedule
FlixBus and Greyhound run 14 direct buses a week from Orangeburg to Charlotte. The fastest takes 2 hours 30 minutes; the first bus leaves at 1:10 PM and the last at 10:00 PM.
Timetable data from · Schedule last changed
- Buses a week
- 14
- Fastest trip
- 2h 30m
- First bus
- 1:10 PM
- Last bus
- 10:00 PM
Timetable
Every bus leaves from Orangeburg (Xpress Travel Center) and arrives at Charlotte Bus Station. Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Bus company |
|---|---|---|---|---|
| 1:10 PM | 4:55 PM | 3h 45m | Daily | Greyhound Full timetable |
| 10:00 PM | 12:30 AM +1 day | 2h 30m | Daily | FlixBus Full timetable |
Route map
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Where to board in Orangeburg Where you get off in Charlotte The route of the busiest trip
Where to catch the bus in Orangeburg
- Orangeburg (Xpress Travel Center) Map of Orangeburg (Xpress Travel Center) (Google Maps)
Where the bus stops in Charlotte
Return trip: Charlotte to Orangeburg
Questions
How long is the bus from Orangeburg to Charlotte?
The fastest direct bus takes 2 hours 30 minutes.
What time is the first bus from Orangeburg to Charlotte?
The earliest departure is at 1:10 PM (Daily) and the last at 10:00 PM (Daily).
Which bus companies go from Orangeburg to Charlotte?
FlixBus and Greyhound run direct buses on this route.
Where do I catch the bus in Orangeburg?
Buses to Charlotte leave from Orangeburg (Xpress Travel Center).