LA → LA · about 126 miles

Opelousas to New Orleans bus schedule

Greyhound runs 12 direct buses a week from Opelousas to New Orleans. The fastest takes 2 hours 40 minutes; the first bus leaves at 11:35 AM and the last at 4:20 PM.

Timetable data from · No schedule changes since at least

Buses a week
12
Fastest trip
2h 40m
First bus
11:35 AM
Last bus
4:20 PM

Timetable

Every bus leaves from Opelousas Texaco and arrives at New Orleans Bus Station. Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.

Direct buses from Opelousas, LA to New Orleans, LA
DepartsArrivesDurationDaysBus company
11:35 AM4:20 PM4h 45mDailyGreyhound
Full timetable
4:20 PM7:00 PM2h 40mMon, Thu, Fri, Sat, SunGreyhound
Full timetable

Route map

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Where to board in Opelousas Where you get off in New Orleans The route of the busiest trip

Where to catch the bus in Opelousas

Where the bus stops in New Orleans

Return trip: New Orleans to Opelousas

Questions

How long is the bus from Opelousas to New Orleans?

The fastest direct bus takes 2 hours 40 minutes.

What time is the first bus from Opelousas to New Orleans?

The earliest departure is at 11:35 AM (Daily) and the last at 4:20 PM (Mon, Thu, Fri, Sat, Sun).

Which bus companies go from Opelousas to New Orleans?

Greyhound runs direct buses on this route.

Where do I catch the bus in Opelousas?

Buses to New Orleans leave from Opelousas Texaco.