LA → LA · about 126 miles

New Orleans to Opelousas bus schedule

Greyhound runs 12 direct buses a week from New Orleans to Opelousas. The fastest takes 3 hours; the first bus leaves at 6:30 AM and the last at 10:55 AM.

Timetable data from · No schedule changes since at least

Buses a week
12
Fastest trip
3h 00m
First bus
6:30 AM
Last bus
10:55 AM

Timetable

Every bus leaves from New Orleans Bus Station and arrives at Opelousas Texaco. Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.

Direct buses from New Orleans, LA to Opelousas, LA
DepartsArrivesDurationDaysBus company
6:30 AM11:05 AM4h 35mDailyGreyhound
Full timetable
10:55 AM1:55 PM3h 00mMon, Tue, Fri, Sat, SunGreyhound
Full timetable

Route map

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Where to board in New Orleans Where you get off in Opelousas The route of the busiest trip

Where to catch the bus in New Orleans

Where the bus stops in Opelousas

Return trip: Opelousas to New Orleans

Questions

How long is the bus from New Orleans to Opelousas?

The fastest direct bus takes 3 hours.

What time is the first bus from New Orleans to Opelousas?

The earliest departure is at 6:30 AM (Daily) and the last at 10:55 AM (Mon, Tue, Fri, Sat, Sun).

Which bus companies go from New Orleans to Opelousas?

Greyhound runs direct buses on this route.

Where do I catch the bus in New Orleans?

Buses to Opelousas leave from New Orleans Union Passenger Terminal.