LA → LA · about 102 miles
Opelousas to Natchitoches bus schedule
Greyhound runs 5 direct buses a week from Opelousas to Natchitoches. The fastest takes 2 hours 5 minutes; every bus leaves at 2:00 PM.
Timetable data from · No schedule changes since at least
- Buses a week
- 5
- Fastest trip
- 2h 05m
- Leaves at
- 2:00 PM
Timetable
Every bus leaves from Opelousas Texaco and arrives at Natchitoches (Bayou Soul). Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Bus company |
|---|---|---|---|---|
| 2:00 PM | 4:05 PM | 2h 05m | Mon, Tue, Fri, Sat, Sun | Greyhound Full timetable |
Route map
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Where to board in Opelousas Where you get off in Natchitoches The route of the busiest trip
Where to catch the bus in Opelousas
- Opelousas Texaco Map of Opelousas Texaco (Google Maps)
Where the bus stops in Natchitoches
- Natchitoches (Bayou Soul) Map of Natchitoches (Bayou Soul) (Google Maps)
Return trip: Natchitoches to Opelousas
Questions
How long is the bus from Opelousas to Natchitoches?
The fastest direct bus takes 2 hours 5 minutes.
What time is the first bus from Opelousas to Natchitoches?
Every departure is at 2:00 PM (Mon, Tue, Fri, Sat, Sun).
Which bus companies go from Opelousas to Natchitoches?
Greyhound runs direct buses on this route.
Where do I catch the bus in Opelousas?
Buses to Natchitoches leave from Opelousas Texaco.