NY → NY · about 138 miles
Niagara Falls to Ithaca bus schedule
FlixBus and OurBus run 12 direct buses a week from Niagara Falls to Ithaca. The fastest takes 4 hours 20 minutes; the first bus leaves at 2:50 AM and the last at 10:40 AM.
Timetable data from · Schedule last changed
- Buses a week
- 12
- Fastest trip
- 4h 20m
- First bus
- 2:50 AM
- Last bus
- 10:40 AM
Timetable
Times are local to each stop. Timetables published by tds.ai, refreshed October 15, 2026. Schedules change, so check times when you book.
| Departs | Arrives | Duration | Days | Stops | Bus company |
|---|---|---|---|---|---|
| 2:50 AM | 7:15 AM | 4h 25m | Mon, Tue, Wed, Sat, Sun | Niagara Falls Old Main St to Ithaca NY (ITH) | FlixBus Full timetable |
| 7:40 AM | 12:00 PM | 4h 20m | Daily from Dec 15 | Niagara Falls, NY (Old Main Street, charter bus zone behind visitor center. One block from Niagara Falls State Park) to Ithaca, NY (Downtown Ithaca - E. Seneca Street in front of Ithaca Deli (Note if arriving by car, use 118 E. Seneca Street for directions)) | OurBus Full timetable |
| 10:40 AM | 3:00 PM | 4h 20m | Daily | Niagara Falls, NY (Old Main Street, charter bus zone behind visitor center. One block from Niagara Falls State Park) to Ithaca, NY (Downtown Ithaca - E. Seneca Street in front of Ithaca Deli (Note if arriving by car, use 118 E. Seneca Street for directions)) | OurBus Full timetable |
Route map
The map needs JavaScript.
Where to board in Niagara Falls Where you get off in Ithaca The route of the busiest trip
Where to catch the bus in Niagara Falls
Where the bus stops in Ithaca
Return trip: Ithaca to Niagara Falls
Questions
How long is the bus from Niagara Falls to Ithaca?
The fastest direct bus takes 4 hours 20 minutes; the typical trip is 4 hours 20 minutes.
What time is the first bus from Niagara Falls to Ithaca?
The earliest departure is at 2:50 AM (Mon, Tue, Wed, Sat, Sun) and the last at 10:40 AM (Daily).
Which bus companies go from Niagara Falls to Ithaca?
FlixBus and OurBus run direct buses on this route.
Where do I catch the bus in Niagara Falls?
Buses to Ithaca leave from Niagara Falls Old Main St.